Article
Mice lacking microRNAs in Pax8-expressing cells develop hypothyroidism and end-stage renal failure.
BMC molecular biology - 18 Apr 2016
Bartram Malte P, Amendola Elena, Benzing Thomas, Schermer Bernhard, de Vita Gabriella, Müller Roman-Ulrich
Abstract excerpt
BACKGROUND: Non-coding RNAs have gained increasing attention during the last decade. The first large group of non-coding RNAs to be characterized systematically starting at the beginning of the 21st century were small oligonucleotides--the so-called microRNAs (miRNAs). By now we have learnt that microRNAs are indispensable for most biological processes including organogenesis and maintenance of organ structure...
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