Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A genetic risk score of 45 coronary artery disease risk variants associates with increased risk of myocardial infarction in 6041 Danish individuals.

Atherosclerosis - 1 Jun 2015

Krarup N T, Borglykke A, Allin K H, Sandholt C H, Justesen J M, Andersson E A, Grarup N, Jørgensen T, Pedersen O, Hansen T

Abstract excerpt

BACKGROUND: In Europeans, 45 genetic risk variants for coronary artery disease (CAD) have been identified in genome-wide association studies. We constructed a genetic risk score (GRS) of these variants to estimate the effect on incidence and clinical predictability of myocardial infarction (MI) and CAD. METHODS: Genotype was available from 6041 Danes. An unweighted GRS was constructed by making a summated score...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Comorbidity
Share to Coronary Artery Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Denmark

Share to Myocardial Infarction

Share to Proportional Hazards Models

Share to Regression Analysis

Share to Risk Reduction Behavior

Share to Smoking

Source

Identifiers

PMID: 25864160
DOI: 10.1016/j.atherosclerosis.2015.03.022

Genes

CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A genetic risk score of 45 coronary artery disease risk variants associates with increased risk of myocardial infarction in 6041 Danish individuals.PMID 25864160Read ↗

A Polygenic Risk Score for Coronary Artery Disease Improves the Prediction of Early-Onset Myocardial Infarction and Mortality in MenSemantic proximity Read ↗

Genomic risk prediction of coronary artery disease in nearly 500,000 adults: implications for early screening and primary preventionSemantic proximity Read ↗

Polygenic risk score and coronary artery disease: A meta-analysis of 979,286 participant data.Semantic proximity Read ↗

Impact of a Genetic Risk Score on Myocardial Infarction Risk Across Different Ethnic Populations.Semantic proximity Read ↗

Prospective association of a genetic risk score with major adverse cardiovascular events in patients with coronary artery disease.Semantic proximity Read ↗

A genetic risk score is associated with incident cardiovascular disease and coronary artery calcium: the Framingham Heart Study.Semantic proximity Read ↗

How close are we to implementing a genetic risk score for coronary heart disease?Semantic proximity Read ↗

Genetic predisposition to coronary artery disease is predictive of recurrent events: a Chinese prospective cohort study.Semantic proximity Read ↗

Clinical and Genomic Prediction of Coronary Artery Disease Subtypes.Semantic proximity Read ↗

Association of a genetic risk score with prevalent and incident myocardial infarction in subjects undergoing coronary angiography.Semantic proximity Read ↗

Prediction of Coronary Artery Disease and Major Adverse Cardiovascular Events Using Clinical and Genetic Risk Scores for Cardiovascular Risk Factors.Semantic proximity Read ↗

Restricted Versus Genome-Wide Genetic Risk Scores for Coronary Artery Disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.