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Genetic predisposition to coronary artery disease is predictive of recurrent events: a Chinese prospective cohort study.

Human molecular genetics - 15 Apr 2020

Jiang Jie, Zheng Qiwen, Han Yaling, Qiao Shubin, Chen Jiyan, Yuan Zuyi, Yu Bo, Ge Lei, Jia Jia, Gong Yanjun, Wang Zhi, Chen Dafang, Zhang Yan, Huo Yong

Abstract excerpt

Evidence of the effects of genetic risk score (GRS) on secondary prevention is scarce and mixed. We investigated whether coronary artery disease (CAD) susceptible loci can be used to predict the risk of major adverse cardiovascular events (MACEs) in a cohort with acute coronary syndromes (ACSs). A total of 1667 patients hospitalized with ACS were enrolled and prospectively followed for a median of 2 years. We...

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Asian People
Coronary Artery Disease
Genetic Markers
Prognosis
Recurrence

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PMID: 32065240
DOI: 10.1093/hmg/ddaa025

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