Article
Association of a genetic risk score with prevalent and incident myocardial infarction in subjects undergoing coronary angiography.
Circulation. Cardiovascular genetics - 1 Aug 2012
Patel Riyaz S, Sun Yan V, Hartiala Jaana, Veledar Emir, Su Shaoyong, Sher Salman, Liu Ying X, Rahman Ayaz, Patel Ronak, Rab S Tanveer, Vaccarino Viola, Zafari A Maziar, Samady Habib, Tang W H Wilson, Allayee Hooman, Hazen Stanley L, Quyyumi Arshed A
Abstract excerpt
BACKGROUND: Genome-wide association studies have identified multiple variants associating with coronary artery disease (CAD) and myocardial infarction (MI). Whether a combined genetic risk score (GRS) is associated with prevalent and incident MI in high-risk subjects remains to be established. METHODS AND RESULTS: In subjects undergoing cardiac catheterization (n=2597), we identified cases with a history of MI...
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