Article
A Thr72Ala polymorphism in the NKG2D gene is associated with early symptomatic congenital cytomegalovirus disease.
Infection - 1 Jun 2015
Taniguchi Rumi, Koyano Shin, Suzutani Tatsuo, Goishi Keiji, Ito Yushi, Morioka Ichiro, Nakamura Hiroyuki, Yamada Hideto, Oka Akira, Inoue Naoki
Abstract excerpt
The potential risk factors for congenital cytomegalovirus (cCMV) infection or development of disease remain unclear. Here, we investigated the genetic polymorphisms in natural killer (NK) group 2, member D (NKG2D), an activating receptor expressed on NK cells, and in MHC class I-related chains A, the ligand of NKG2D, in 87 cCMV cases, and found that there was a significant association between cCMV disease and a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
