Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

NKG2C Sequence Polymorphism Modulates the Expansion of Adaptive NK Cells in Response to Human CMV.

HLA - 1 Nov 2024

Asenjo Judit, Moraru Manuela, Al-Akioui-Sanz Karima, Altadill Mireia, Muntasell Aura, López-Botet Miguel, Vilches Carlos

Abstract excerpt

A subpopulation of NK cells with distinctive phenotype and function differentiates and expands specifically in response to infection by human cytomegalovirus (HCMV). A hallmark of these adaptive NK cells is their increased expression levels of the activating CD94/NKG2C receptor for HLA-E, and lack of expression of its inhibitory homologue CD94/NKG2A. Their frequency is highly variable in HCMV+ individuals, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Adaptive Immunity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytomegalovirus

Share to Cytomegalovirus Infections

Share to HLA-E Antigens

Share to Killer Cells, Natural

Share to NK Cell Lectin-Like Receptor Subfamily C

Share to Promoter Regions, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 39581700
DOI: 10.1111/tan.15764
PMCID: PMC11586157

Genes

KLRC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

NKG2C Sequence Polymorphism Modulates the Expansion of Adaptive NK Cells in Response to Human CMV.PMID 39581700Read ↗

NKG2C zygosity influences CD94/NKG2C receptor function and the NK‐cell compartment redistribution in response to human cytomegalovirusSemantic proximity Read ↗

Adaptive reconfiguration of the human NK‐cell compartment in response to cytomegalovirus: A different perspective of the host‐pathogen interactionSemantic proximity Read ↗

Relationship of NKG2C Copy Number with the Distribution of Distinct Cytomegalovirus-Induced Adaptive NK Cell SubsetsSemantic proximity Read ↗

Diversity of NKG2C genotypes in a European population: Conserved and recombinant haplotypes in the coding, promoter, and 3'-untranslated regions.Semantic proximity Read ↗

Spotlight on NKG 2 C and the human NK ‐cell response to CMV infectionSemantic proximity Read ↗

HLA-E Peptide Repertoire and Dimorphism—Centerpieces in the Adaptive NK Cell Puzzle?Semantic proximity Read ↗

Imprint of human cytomegalovirus infection on the NK cell receptor repertoire.Semantic proximity Read ↗

Influence of human cytomegalovirus infection on the NK cell receptor repertoire in childrenSemantic proximity Read ↗

Activating KIRs and NKG2C in Viral Infections: Toward NK Cell Memory?Semantic proximity Read ↗

Influence of congenital human cytomegalovirus infection and the NKG2C genotype on NK‐cell subset distribution in childrenSemantic proximity Read ↗

Polygenic polymorphism is associated with NKG2A repertoire and influences lymphocyte phenotype and function.Semantic proximity Read ↗

Adaptive NKG2C+ NK Cell Response and the Risk of Cytomegalovirus Infection in Kidney Transplant Recipients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.