Article
Human cytomegalovirus UL144 gene polymorphisms in congenital infections.
Journal of clinical microbiology - 1 Jan 2005
Picone Olivier, Costa Jean-Marc, Chaix Marie-Laure, Ville Yves, Rouzioux Christine, Leruez-Ville Marianne
Abstract excerpt
The human cytomegalovirus (HCMV) UL144 gene is a tumor necrosis factor-like receptor with the potential to affect HCMV virulence. HCMV strains display genetic variability in the UL144 region, and the analysis of a potential link between UL144 gene polymorphisms and disease severity has scarcely been studied. However, a correlation between the UL144 genotype and congenital-disease outcome has been reported in one...
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