Article
Association of NKG2D genetic polymorphism with susceptibility to chronic hepatitis B in a Han Chinese population.
Journal of medical virology - 1 Sept 2010
Ma Juan, Guo Xinhui, Wu Xiaopan, Li Junhong, Zhu Xilin, Li Zhuo, Li Jingyun, Pan Liping, Li Tianjie, Li Hui, Liu Ying
Abstract excerpt
Natural killer (NK) cells are important antiviral effectors of innate immunity because of their contribution to virus elimination. NK cell-mediated immunological reaction to hepatitis B virus (HBV) infection depends on a fine balance between inhibitory and activating receptors. The aim of the study was to investigate genetic polymorphisms in NK cell receptors (NKR)-KLRD1 (CD94), KLRK1 (NKG2D), KLRC4 (NKG2F), and...
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