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Influence of congenital human cytomegalovirus infection and the NKG2C genotype on NK‐cell subset distribution in children

11 Sept 2012

Abstract excerpt

Human cytomegalovirus (HCMV) has been reported to reshape the NK-cell receptor (NKR) distribution, promoting an expansion of CD94/NKG2C(+) NK and T cells. The role of NK cells in congenital HCMV infection is ill-defined. Here we studied the expression of NKR (i.e., NKG2C, NKG2A, LILRB1, CD161) and the frequency of the NKG2C gene deletion in children with past congenital infection, both symptomatic (n = 15) and...

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Identifiers

PMID: 22965785
DOI: 10.1002/eji.201242752

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