Article
Polymorphisms in TLR-2 are associated with congenital cytomegalovirus (CMV) infection but not with congenital CMV disease.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Dec 2013
Taniguchi Rumi, Koyano Shin, Suzutani Tatsuo, Goishi Keiji, Ito Yushi, Morioka Ichiro, Oka Akira, Nakamura Hiroyuki, Yamada Hideto, Igarashi Takashi, Inoue Naoki
Abstract excerpt
BACKGROUND: Cytomegalovirus (CMV) is the most common cause of congenital virus infection. However, the risk factors for infection in utero and for progression to a severe clinical outcome remain uncertain. Recent studies have identified associations of specific single nucleotide polymorphisms (SNPs) in Toll-like receptor (TLR) genes with susceptibility to infections of some viruses and with their clinical...
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