Article
TLR9 2848 GA heterozygotic status possibly predisposes fetuses and newborns to congenital infection with human cytomegalovirus.
PloS one - 1 Jan 2015
Wujcicka Wioletta, Paradowska Edyta, Studzińska Mirosława, Gaj Zuzanna, Wilczyński Jan, Leśnikowski Zbigniew, Nowakowska Dorota
Abstract excerpt
BACKGROUND: Some single nucleotide polymorphisms (SNP), located in Toll-like receptor (TLR) genes, were reported to be associated with human cytomegalovirus (HCMV) infections. The study was aimed to assess the correlation of SNPs at TLR4 and TLR9 genes with the occurrence of congenital cytomegaly, based on available samples. METHODS: Reported case-control study included both HCMV infected and non-infected fetuses...
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