Article
Mutational status of naevus-associated melanomas.
The British journal of dermatology - 1 Sept 2015
Shitara D, Tell-Martí G, Badenas C, Enokihara M M S S, Alós L, Larque A B, Michalany N, Puig-Butille J A, Carrera C, Malvehy J, Puig S, Bagatin E
Abstract excerpt
BACKGROUND: The origin of melanoma has always been a debated subject, as well as the role of adjacent melanocytic naevi. Epidemiological and histopathological studies point to melanomas arising either de novo or from a naevus. OBJECTIVES: To evaluate the presence of mutations in genes from well-known melanomagenesis pathways in a large series of naevus-associated melanomas. MATERIALS AND METHODS: Sixty-one...
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