Article
ESP, EORTC, and EURACAN Expert Opinion: practical recommendations for the pathological diagnosis and clinical management of intermediate melanocytic tumors and rare related melanoma variants.
Virchows Archiv : an international journal of pathology - 1 Jul 2021
de la Fouchardiere Arnaud, Blokx Willeke, van Kempen Léon C, Luzar Boštjan, Piperno-Neumann Sophie, Puig Susana, Alos Llucia, Calonje Eduardo, Massi Daniela
Abstract excerpt
The recent WHO classification of skin tumors has underscored the importance of acknowledging intermediate grade melanocytic proliferations. A multistep acquisition of oncogenic events drives the progressive transformation of nevi into melanomas. The various pathways described are modulated by the initial oncogenic drivers that define the common, blue, and Spitz nevi groups. Intermediate lesions are most often the...
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