Article
Clinicopathologic and genetic characterization of invasive melanoma with BRAF V600K mutation: A study of 16 cases.
Journal of cutaneous pathology - 1 Aug 2023
Goto Keisuke, Yoshikawa Shusuke, Takai Toshihiro, Tachibana Kota, Honma Keiichiro, Isei Taiki, Kukita Yoji, Oishi Takuma
Abstract excerpt
BACKGROUND: The clinicopathologic and genetic features of cutaneous melanoma with a BRAF V600K mutation are not well-known. We aimed to evaluate these characteristics in comparison with those associated with BRAF V600E. METHODS: Real-time polymerase chain reaction (PCR) and/or the MassARRAY® system were used to detect BRAF V600K in 16 invasive melanomas and confirm BRAF V600E in another 60 cases....
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