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Article

Genomic heterogeneity of osteosarcoma - shift from single candidates to functional modules.

PloS one - 1 Jan 2015

Poos Kathrin, Smida Jan, Maugg Doris, Eckstein Gertrud, Baumhoer Daniel, Nathrath Michaela, Korsching Eberhard

Abstract excerpt

Osteosarcoma (OS), a bone tumor, exhibit a complex karyotype. On the genomic level a highly variable degree of alterations in nearly all chromosomal regions and between individual tumors is observable. This hampers the identification of common drivers in OS biology. To identify the common molecul...

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Identifiers

PMID: 25848766
DOI: 10.1371/journal.pone.0123082
PMCID: PMC4388529

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25848766-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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