Article

The variable genomic landscape during osteosarcoma progression: insights from a longitudinal WGS analysis

2024-04-19

Abstract excerpt

Osteosarcoma is a primary bone tumor that exhibits a complex genome characterized by gross chromosomal abnormalities. Osteosarcoma patients often develop metastatic disease, resulting in limited therapeutic options and poor survival rates. To gain knowledge on the mechanisms underlying osteosarcoma heterogeneity and metastatic process, it is important to obtain a detailed profile of the genomic alterations that ac...

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Literature Corpus work: 2c87a7d5-6a2e-597d-ada8-80b9fdeeae49
DOI: 10.1101/2024.04.18.24306025

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