Article
Osteosarcoma's genetic landscape painted by genes' mutations.
Acta biochimica Polonica - 17 Sept 2023
Urban Wiktoria, Krzystańska Dagmara, Piekarz Michał, Nazar Jerzy, Jankowska Anna
Abstract excerpt
PURPOSE: Osteosarcoma (OS) is one of the most common primary bone tumors. Direct pathogenesis remains unknown, however, genes' mutations are proven to participate in the process. This study aimed to examine the most frequently mutated genes in OS to appoint candidates for the cancer markers. METHODS: Using the COSMIC Catalogue twenty the most frequently mutated genes were selected leading to an up-to-date genetic...
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