Article
Single nucleotide polymorphisms in the FAM167A-BLK gene are associated with polymyositis/dermatomyositis in the Han Chinese population.
Immunologic research - 1 Jun 2015
Chen Si, Wu Wei, Li Jing, Wang Qian, Li Yuan, Wu Ziyan, Zheng Wenjie, Wu Qingjun, Wu Chanyuan, Zhang Fengchun, Li Yongzhe
Abstract excerpt
Idiopathic inflammatory myopathies (IIMs) are autoimmune diseases influenced by genetic background and environmental factors. Recently, FAM167A-BLK gene has been identified as a potential genetic susceptibility locus for dermatomyositis (DM) in patients of European and Japanese populations. Our aim here was to investigate the association between FAM167A-BLK polymorphisms and IIMs risk in Chinese Han. The...
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