Article

Genome-wide DNA methylation and mRNA transcription analysis revealed aberrant gene regulation pathways in dermatomyositis and polymyositis patients

2023-01-13

Abstract excerpt

<h4>Objectives: </h4> Idiopathic inflammatory myopathies (IIM) are a group of refractory systemic autoimmune diseases with unknown pathogenesis, including dermatomyositis (DM) and polymyositis (PM). DNA methylation is an important epigenetic mechanism to regulate gene expression, which plays important roles in IIM. Integrated analysis of the whole-genome DNA methylation and gene expression profiling will provide a...

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Literature Corpus work: a5435502-782c-525c-9c0a-b6e385777be4
DOI: 10.21203/rs.3.rs-2378508/v1

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