Article
Association between a C8orf13-BLK polymorphism and polymyositis/dermatomyositis in the Japanese population: an additive effect with STAT4 on disease susceptibility.
PloS one - 1 Jan 2014
Sugiura Tomoko, Kawaguchi Yasushi, Goto Kanako, Hayashi Yukiko, Gono Takahisa, Furuya Takefumi, Nishino Ichizo, Yamanaka Hisashi
Abstract excerpt
BACKGROUND: Accumulating evidence has shown that several non-HLA genes are involved in the susceptibility to polymyositis/dermatomyositis. This study aimed to investigate the involvement of C8orf13-BLK, one of the strongest candidate genes for autoimmune diseases, in susceptibility to polymyositis/dermatomyositis in the Japanese population. A possible gene-gene interaction between C8orf13-BLK and STAT4, which we...
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