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Article

Positive association of genetic variations in the phospholipase C-like 1 gene with dermatomyositis in Chinese Han.

Immunologic research - 1 Feb 2016

Wang Qian, Chen Si, Li Yuan, Li Ping, Wu Chanyuan, Wu Ziyan, Wu Qingjun, Sun Fei, Li Jing, Zheng Wenjie, Deng Chuiwen, Zhang Fengchun, Li Yongzhe

Abstract excerpt

Idiopathic inflammatory myopathies (IIMs) are autoimmune diseases with an underlying yet undefined genetic component. Recently, phospholipase C-like 1 (PLCL1) has been identified as a potential genetic susceptibility locus for dermatomyositis (DM) in patients of European ancestry. Here, association between PLCL1 polymorphisms and IIMs was investigated in Chinese Han. Genomic DNA was isolated from blood samples (2...

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Source

Identifiers

PMID: 26603167
DOI: 10.1007/s12026-015-8738-x

Genes

PLCL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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