Article
Genetic association study of TNFAIP3, IFIH1, IRF5 polymorphisms with polymyositis/dermatomyositis in Chinese Han population.
PloS one - 1 Jan 2014
Chen Si, Wang Qian, Wu Ziyan, Li Yuan, Li Ping, Sun Fei, Zheng Wenjie, Wu Qingjun, Wu Chanyuan, Deng Chuiwen, Zhang Fengchun, Li Yongzhe
Abstract excerpt
BACKGROUND: Single-nucleotide polymorphisms (SNPs) in the TNFAIP3, IFIH1, and IRF5 genes have been associated with several auto-inflammation diseases, while the susceptibility between these genes and idiopathic inflammatory myopathies (IIMs) were not reported. This study aimed to investigate whether TNFAIP3, IFIH1, and IRF5 gene polymorphisms confer susceptibility for the IIMs in Chinese Han population. METHODS:...
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