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Article

Double hit diffuse large B-cell lymphomas: diagnostic and therapeutic challenges.

Chinese clinical oncology - 1 Mar 2015

Friedberg Jonathan W

Abstract excerpt

Although diffuse large B-cell lymphoma (DLBCL) is curable with standard chemoimmunotherapy, over 30% of patients with advanced stage disease experience refractory disease or progression. Recent studies suggest that rearrangement of the myc oncogene occurs in approximately 10% of patients with DLBCL, and confers a very poor prognosis, particularly when there is concomitant rearrangement of bcl-2, a condition...

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Share to Antineoplastic Combined Chemotherapy Protocols
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Share to Lymphoma, Large B-Cell, Diffuse

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25841716
DOI: 10.3978/j.issn.2304-3865.2015.03.02

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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