Article
Double hit lymphoma: How do we define it and how do we treat it?
Best practice & research. Clinical haematology - 1 Sept 2018
Merron Brídgín, Davies Andrew
Abstract excerpt
Double/triple hit lymphoma is recognised as a distinct entity within the heterogeneous group of high grade B-cell lymphomas, accounting for between 5 and 10% of cases of diffuse large B-cell lymphoma. Under the WHO 2016 it is now known as high-grade B-cell lymphoma with rearrangements of MYC and BCL2 and/or BCL6. When treated with standard chemotherapy it has a poor outcome. There is currently no standard of care...
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