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Altered pathways and targeted therapy in double hit lymphoma

18 Mar 2022

Abstract excerpt

High-grade B-cell lymphoma with translocations involving MYC and BCL2 or BCL6, usually referred to as double hit lymphoma (DHL), is an aggressive hematological malignance with distinct genetic features and poor clinical prognosis. Current standard chemoimmunotherapy fails to confer satisfying outcomes and few targeted therapeutics are available for the treatment against DHL. Recently, the delineating of the...

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CAR-T cell therapy research
Lymphoma Diagnosis and Treatment
Protein Degradation and Inhibitors

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 35303910
DOI: 10.1186/s13045-022-01249-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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