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Article

Double-Hit Large B Cell Lymphoma.

Current oncology reports - 26 Sept 2017

Khelfa Yousef, Lebowicz Yehuda, Jamil Muhammad Omer

Abstract excerpt

Diffuse large B cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma (NHL), accounting for approximately 25% of NHL cases. It is a heterogeneous group of diseases. BCL2, BCL6, and MYC are the most frequent mutated genes in DLBCL. Double-hit lymphoma (DHL) is an aggressive form of DLBCL with an unmet treatment need, in which MYC rearrangement is present with either BCL2 or BCL6 rearrangement....

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Source

Identifiers

PMID: 28952038
DOI: 10.1007/s11912-017-0629-y

Genes

BCL2
BCL6
MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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