Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The effects of the CACNA1C rs1006737 A/G on affective startle modulation in healthy males.

European psychiatry : the journal of the Association of European Psychiatrists - 1 Jun 2015

Pasparakis E, Koiliari E, Zouraraki C, Tsapakis E-M, Roussos P, Giakoumaki S G, Bitsios P

Abstract excerpt

BACKGROUND: The CACNA1C rs1006737 risk A allele has been associated with affective psychoses and functional studies indicate that it is associated with increased hippocampal/amygdala activity during emotional face-processing. Here we studied the impact of the risk A allele on affective startle modulation. METHODS: Hundred and ninety-four healthy males stratified for their CACNA1C rs1006737 genotype (GG:111,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Alleles
Share to Calcium Channels, L-Type
Share to Mood Disorders
Share to Neuropsychological Tests
Share to Personality
Share to Reflex, Startle
Share to Risk Factors
Share to Young Adult

Source

Identifiers

PMID: 25841664
DOI: 10.1016/j.eurpsy.2015.03.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The effects of the CACNA1C rs1006737 A/G on affective startle modulation in healthy males.PMID 25841664Read ↗

ADORA2A Gene variation, caffeine, and emotional processing: a multi-level interaction on startle reflex.Semantic proximity Read ↗

The CACNA1C and ANK3 risk alleles impact on affective personality traits and startle reactivity but not on cognition or gating in healthy males.Semantic proximity Read ↗

Serotonin transporter gene variation impacts innate fear processing: Acoustic startle response and emotional startle.Semantic proximity Read ↗

'Negativity bias' in risk for depression and anxiety: brain-body fear circuitry correlates, 5-HTT-LPR and early life stress.Semantic proximity Read ↗

COMT genetic variation affects fear processing: psychophysiological evidence.Semantic proximity Read ↗

Serotonin transporter gene variation and stressful life events impact processing of fear and anxiety.Semantic proximity Read ↗

Genetics of human startle reactivity: A systematic review to acquire targets for an anxiety endophenotype.Semantic proximity Read ↗

The effect of polymorphisms in startle-related genes on anxiety symptom severity.Semantic proximity Read ↗

Modification of caffeine effects on the affect-modulated startle by neuropeptide S receptor gene variation.Semantic proximity Read ↗

CACNA1C risk variant and amygdala activity in bipolar disorder, schizophrenia and healthy controls.Semantic proximity Read ↗

Innate fear responses are reflected in the blood epigenome of rhesus macaquesSemantic proximity Read ↗

CACNA1C risk variant affects facial emotion recognition in healthy individuals.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.