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Article

The CACNA1C and ANK3 risk alleles impact on affective personality traits and startle reactivity but not on cognition or gating in healthy males.

Bipolar disorders - 1 May 2011

Roussos Panos, Giakoumaki Stella G, Georgakopoulos Anastasios, Robakis Nikolaos K, Bitsios Panos

Abstract excerpt

OBJECTIVES: The rs10994336 ANK3 and rs1006737 CACNA1C genetic variants have recently been identified as the most consistent, genome-wide significant risk factors for bipolar disorder, while the CACNA1C variant has also been associated with schizophrenia and major depression. The aim of this study was to examine the phenotypic consequences of the risk CACNA1C and ANK3 alleles in a large homogeneous cohort of...

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Source

Identifiers

PMID: 21676128
DOI: 10.1111/j.1399-5618.2011.00924.x

Genes

ANK3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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