ADORA2A Gene variation, caffeine, and emotional processing: a multi-level interaction on startle reflex.

doi:10.1038/npp.2011.253

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Article

ADORA2A Gene variation, caffeine, and emotional processing: a multi-level interaction on startle reflex.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Feb 2012

Domschke Katharina, Gajewska Agnieszka, Winter Bernward, Herrmann Martin J, Warrings Bodo, Mühlberger Andreas, Wosnitza Katherina, Glotzbach Evelyn, Conzelmann Annette, Dlugos Andrea, Fobker Manfred, Jacob Christian, Arolt Volker, Reif Andreas, Pauli Paul, Zwanzger Peter, Deckert Jürgen

Abstract excerpt

There is converging evidence for genetic, biochemical, and neuropsychological factors to increase the risk for anxiety and anxiety disorders. The pathogenesis of anxiety disorders is assumed to be influenced by a complex interaction of these individual risk factors on several levels, affecting intermediate phenotypes of anxiety such as the startle reflex. Thus, in the present double-blind, placebo-controlled...

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PMID: 22012471
DOI: 10.1038/npp.2011.253
PMCID: PMC3260968

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