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Article

COMT genetic variation affects fear processing: psychophysiological evidence.

Behavioral neuroscience - 1 Aug 2008

Montag Christian, Buckholtz Joshua W, Hartmann Peter, Merz Michael, Burk Christian, Hennig Juergen, Reuter Martin

Abstract excerpt

Emotional dysregulation is a core characteristic of many psychiatric diseases, including the anxiety disorders. Although heritable influences account for a significant degree of variation in risk for such disorders, relatively few candidate susceptibility factors have been identified. A coding variant in one such gene, encoding the dopamine catabolic enzyme catechol-O-methyltransferase (COMT Val158Met), has...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18729643
DOI: 10.1037/0735-7044.122.4.901

Genes

COMT
DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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