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Article

PTPRD is homozygously deleted and epigenetically downregulated in human hepatocellular carcinomas.

Omics : a journal of integrative biology - 1 Apr 2015

Acun Tolga, Demir Kubilay, Oztas Emin, Arango Diego, Yakicier M Cengiz

Abstract excerpt

PTPRD (protein tyrosine phosphatase, receptor type, D) is a tumor suppressor gene, frequently inactivated through deletions or epigenetic mechanisms in several cancers with importance for global health. In this study, we provide new and functionally integrated evidence on genetic and epigenetic alterations of PTPRD gene in hepatocellular carcinomas (HCCs). Importantly, HCC is the sixth most common malignancy and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25831062
DOI: 10.1089/omi.2015.0010

Genes

PTPRD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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PTPRD is homozygously deleted and epigenetically downregulated in human hepatocellular carcinomas.PMID 25831062Read ↗

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