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Article

Succinate dehydrogenase B: a new prognostic biomarker in clear cell renal cell carcinoma.

Human pathology - 1 Jun 2015

Cornejo Kristine M, Lu Min, Yang Ping, Wu Shulin, Cai Chao, Zhong Wei-de, Olumi Aria, Young Robert H, Wu Chin-Lee

Abstract excerpt

Succinate dehydrogenase B (SDHB) is a mitochondrial enzyme complex subunit. Loss of SDHB protein expression has been found to correlate with SDHx gene mutations. Little is known about its expression in subtypes of renal cell carcinoma (RCC) and whether it is a prognostic indicator. Four hundred fifty renal epithelial neoplasms were analyzed for SDHB, comprising clear cell RCC (CCRCC) (n = 240), papillary RCC (n =...

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Source

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Identifiers

PMID: 25827535
DOI: 10.1016/j.humpath.2015.02.013
PMCID: PMC4426248

Genes

SDHB
VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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