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New Insights Into Succinate Dehydrogenase-Deficient Renal Cell Carcinoma: A Comprehensive Analysis of a Case Series With Novel Mutation Sites.

Archives of pathology & laboratory medicine - 21 Nov 2025

Wu Junfeng, Wang Yilin, Yang Li, Wang Yingmei, Hu Peizhen, Fan Linni, Xu Yuqiao

Abstract excerpt

Context.—: Succinate dehydrogenase-deficient renal cell carcinoma (RCC) is a newly classified subtype of RCC in the World Health Organization classification of urinary and male genital tumours. However, systemic reports on this tumor are limited. Objective.—: To give new insights into the clinicopathologic and molecular features of succinate dehydrogenase complex iron sulfur subunit B (SDHB)-deficient RCC....

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Identifiers

PMID: 41269775
DOI: 10.5858/arpa.2025-0233-OA

Genes

SDHB

Variants

Provenance

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