Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Novel SDHA-deficient Renal Cell Carcinoma Revealed by Comprehensive Genomic Profiling

12 Feb 2015

Abstract excerpt

Succinate dehydrogenase (SDH)-deficient renal cell carcinoma (RCC) is an emerging provisional entity included in the 2013 International Society of Urological Pathology Vancouver Classification. Most genomic alterations in patients with SDH-deficient RCCs involve the SDHB subunit, and the associated renal tumors have loss of immunohistochemical SDHB expression and distinctive morphologic features. Renal tumors...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Hypoxia, and Metabolism
Share to Epigenetics and DNA Methylation
Share to Renal cell carcinoma treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25724004
DOI: 10.1097/pas.0000000000000403

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Novel SDHA-deficient Renal Cell Carcinoma Revealed by Comprehensive Genomic ProfilingPMID 25724004Read ↗

Renal carcinoma associated with a novel succinate dehydrogenase A mutation: a case report and review of literature of a rare subtype of renal carcinoma.Semantic proximity Read ↗

SDH-deficient renal cell carcinoma associated with biallelic mutation in succinate dehydrogenase A: comprehensive genetic profiling and its relation to therapy responseSemantic proximity Read ↗

Succinate dehydrogenase A deficient renal cell carcinoma: A rare renal tumor distinct from typical Succinate dehydrogenase deficient renal cell carcinoma.Semantic proximity Read ↗

New Insights Into Succinate Dehydrogenase-Deficient Renal Cell Carcinoma: A Comprehensive Analysis of a Case Series With Novel Mutation Sites.Semantic proximity Read ↗

Single nucleotide variants of succinate dehydrogenase A gene in renal cell carcinoma.Semantic proximity Read ↗

Review of succinate dehydrogenase-deficient renal cell carcinoma with focus on clinical and pathobiological aspects.Semantic proximity Read ↗

Genomic and Metabolic Hallmarks of SDH- and FH-deficient Renal Cell CarcinomasSemantic proximity Read ↗

Genomic and Metabolic Hallmarks of SDH- and FH-Deficient Renal Cell CarcinomasSemantic proximity Read ↗

Succinate Dehydrogenase-Deficient Renal Cancer Featuring Fructose-1, 6-Biphosphatase Loss, Pyruvate Kinase M2 Overexpression, and SWI / SNF Chromatin Remodeling Complex Aberrations: A Rare Case ReportSemantic proximity Read ↗

Genomic alterations and diagnosis of renal cancerSemantic proximity Read ↗

Functional succinate dehydrogenase deficiency is a common adverse feature of clear cell renal cancer.Semantic proximity Read ↗

The Role of the Surgical Pathologist in the Recognition of Hereditary SDH-Deficient Tumor Syndromes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.