Article
Multidrug evolutionary strategies to reverse antibiotic resistance.
Science (New York, N.Y.) - 1 Jan 2016
Baym Michael, Stone Laura K, Kishony Roy
Abstract excerpt
Antibiotic treatment has two conflicting effects: the desired, immediate effect of inhibiting bacterial growth and the undesired, long-term effect of promoting the evolution of resistance. Although these contrasting outcomes seem inextricably linked, recent work has revealed several ways by which antibiotics can be combined to inhibit bacterial growth while, counterintuitively, selecting against resistant...
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