Article
Imputation of class I and II HLA loci using high-density SNPs from ImmunoChip and their associations with Kawasaki disease in family-based study.
International journal of immunogenetics - 1 Jun 2015
Shrestha S, Wiener H W, Aissani B, Shendre A, Tang J, Portman M A
Abstract excerpt
Kawasaki disease (KD) is the leading cause of acquired heart disease in children in most developed countries including the United States. The etiology of KD is not known; however, epidemiological and immunological data suggest infectious or immune-related factors in the manifestation of the disease. Further, KD has several hereditary features that strongly suggest a genetic component to disease pathogenesis....
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