HLA-DRB1*15:01 Is Associated and Linked With Kawasaki Disease, With DRB1*14:01 Conferring Risk to Coronary Artery Lesions: Case-Control and Family-Based Studies.

doi:10.1111/tan.70490

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

HLA-DRB115:01 Is Associated and Linked With Kawasaki Disease, With DRB114:01 Conferring Risk to Coronary Artery Lesions: Case-Control and Family-Based Studies.

HLA - 1 Dec 2025

Chi Hsin, Yang Horng-Woei, Lee Yann-Jinn, Chang Lung, Chen Ming-Ren, Huang Fu-Yuan, Huang Daniel Tsung-Ning, Huang Ching-Ying, Hu Kuang-Chun, Chiu Nan-Chang

Abstract excerpt

Kawasaki disease (KD), also known as mucocutaneous lymph node syndrome, is a leading cause of vasculitis in children aged < 5 years. The HLA complex has been investigated for its association with KD since 1978 without conclusive results due to limitations such as small sample sizes. This study aimed to evaluate the associations and genetic linkage between HLA-DRB1 and KD, as well as its complications. The...

Read the complete abstract on PubMed

Topics

Humans
Mucocutaneous Lymph Node Syndrome
HLA-DRB1 Chains
Male
Female
Case-Control Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Genetic Predisposition to Disease

Child, Preschool

Gene Frequency

Infant

Alleles

Child

Coronary Artery Disease

Genotype

Risk Factors

Linkage Disequilibrium

Source

Open in PubMed Open full text

Identifiers

PMID: 41314210
DOI: 10.1111/tan.70490
PMCID: PMC12662658

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HLA-DRB1*15:01 Is Associated and Linked With Kawasaki Disease, With DRB1*14:01 Conferring Risk to Coronary Artery Lesions: Case-Control and Family-Based Studies.PMID 41314210Read ↗

A genome-wide association analysis identifies NMNAT2 and HCP5 as susceptibility loci for Kawasaki disease.Semantic proximity Read ↗

Human lymphocyte antigen B-associated transcript 2, 3, and 5 polymorphisms and haplotypes are associated with susceptibility of Kawasaki disease and coronary artery aneurysm.Semantic proximity Read ↗

A genome-wide association analysis reveals 1p31 and 2p13.3 as susceptibility loci for Kawasaki disease.Semantic proximity Read ↗

The IL-1B Gene Polymorphisms rs16944 and rs1143627 Contribute to an Increased Risk of Coronary Artery Lesions in Southern Chinese Children with Kawasaki DiseaseSemantic proximity Read ↗

Major histocompatibility complex class I chain-related gene polymorphisms: associated with susceptibility to Kawasaki disease and coronary artery aneurysms.Semantic proximity Read ↗

Imputation of class I and II HLA loci using high-density SNPs from ImmunoChip and their associations with Kawasaki disease in family-based study.Semantic proximity Read ↗

BTNL2 gene polymorphisms may be associated with susceptibility to Kawasaki disease and formation of coronary artery lesions in Taiwanese children.Semantic proximity Read ↗

Genetic variations of HLA-DRB1 and susceptibility to Kawasaki disease in Taiwanese children.Semantic proximity Read ↗

Whole-Exome sequencing reveals Kawasaki disease susceptibility genes and their association with coronary artery lesionSemantic proximity Read ↗

A genome-wide association study identifies novel and functionally related susceptibility Loci for Kawasaki disease.Semantic proximity Read ↗

Genetic variations in the receptor-ligand pair CCR5 and CCL3L1 are important determinants of susceptibility to Kawasaki disease.Semantic proximity Read ↗

Validation of genome-wide associated variants for Kawasaki disease in a Taiwanese case-control sample.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.