Article
Whole-exome sequencing analysis identifies novel variants associated with Kawasaki disease susceptibility.
Pediatric rheumatology online journal - 7 Aug 2023
Zhang Xing, Sun Ying, Meng Lijuan, Ye Caixia, Han Huifeng, Zhang Tiesong, Feng Yue, Li Jianxiao, Duan Lifen, Chen Yanfei
Abstract excerpt
BACKGROUND: Kawasaki disease (KD) is an acute pediatric vasculitis affecting genetically susceptible infants and children. Although the pathogenesis of KD remains unclear, growing evidence links genetic susceptibility to the disease. METHODS: To explore the genes associated with susceptibility in KD, we applied whole-exome sequencing to KD and control subjects from Yunnan province, China. We conducted association...
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