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Article

High-density genotyping of immune loci in Kawasaki disease and IVIG treatment response in European-American case-parent trio study.

Genes and immunity - 1 Dec 2014

Shendre A, Wiener H W, Zhi D, Vazquez A I, Portman M A, Shrestha S

Abstract excerpt

Kawasaki disease (KD) is a diffuse and acute small-vessel vasculitis observed in children, and has genetic and autoimmune components. We genotyped 112 case-parent trios of European decent (confirmed by ancestry informative markers) using the immunoChip array, and performed association analyses with susceptibility to KD and intravenous immunoglobulin (IVIG) non-response. KD susceptibility was assessed using the...

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Identifiers

PMID: 25101798
DOI: 10.1038/gene.2014.47
PMCID: PMC4257866

Genes

CDH22
FUT1

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