Article
A genomewide linkage analysis of Kawasaki disease: evidence for linkage to chromosome 12.
Journal of human genetics - 1 Jan 2007
Onouchi Yoshihiro, Tamari Mayumi, Takahashi Atsushi, Tsunoda Tatsuhiko, Yashiro Mayumi, Nakamura Yoshikazu, Yanagawa Hiroshi, Wakui Keiko, Fukushima Yoshimitsu, Kawasaki Tomisaku, Nakamura Yusuke, Hata Akira
Abstract excerpt
Kawasaki disease (KD) is an acute systemic vasculitis syndrome that primarily affects infants and young children. The cause of KD is largely unknown, but its higher incidence in the Asian population and increased risk in patients' families suggests the existence of underlying genetic factors. To determine the loci of a susceptibility gene for KD, a genomewide linkage analysis with affected sib pairs was performed...
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