Article
Genetic variants in the HLA-G region are associated with Kawasaki disease.
Human immunology - 1 Dec 2008
Kim Jae-Jung, Hong Soo-Jong, Hong Young Mi, Kim Sun, Kang Mi-Jin, Kim Kwi-Joo, Seo Eul-Joo, Yoo Han-Wook, Cheong Hyun-Sub, Shin Hyoung-Doo, Park In-Sook, Lee Jong-Keuk
Abstract excerpt
Kawasaki disease is an acute, self-limited vasculitis of infants and children, manifest as fever and signs of mucocutaneous inflammation. Treatment with high-dose immunoglobulin reduces systemic inflammation and prevents coronary artery lesions in Kawasaki disease. In this study, we investigated the possible association of the major histocompatibililty complex (MHC) region for the susceptibility to Kawasaki...
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