Article
A genome-wide association analysis identifies NMNAT2 and HCP5 as susceptibility loci for Kawasaki disease.
Journal of human genetics - 1 Dec 2017
Kim Jae-Jung, Yun Sin Weon, Yu Jeong Jin, Yoon Kyung Lim, Lee Kyung-Yil, Kil Hong-Ryang, Kim Gi Beom, Han Myung-Ki, Song Min Seob, Lee Hyoung Doo, Ha Kee Soo, Sohn Sejung, Johnson Todd A, Takahashi Atsushi, Kubo Michiaki, Tsunoda Tatsuhiko, Ito Kaoru, Onouchi Yoshihiro, Hong Young Mi, Jang Gi Young, Lee Jong-Keuk
Abstract excerpt
Kawasaki disease (KD), a systemic vasculitis of infants and children, manifests as fever and mucocutaneous inflammation. Although its etiology is largely unknown, the epidemiological data suggest that genetic factors are important in KD susceptibility. To identify genetic variants influencing KD susceptibility, we performed a genome-wide association study (GWAS) and replication study using a total of 915 children...
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