Article
A genome-wide association analysis reveals 1p31 and 2p13.3 as susceptibility loci for Kawasaki disease.
Human genetics - 1 May 2011
Kim Jae-Jung, Hong Young Mi, Sohn Saejung, Jang Gi Young, Ha Kee-Soo, Yun Sin Weon, Han Myung Ki, Lee Kyung-Yil, Song Min Seob, Lee Hyoung Doo, Kim Dong Soo, Lee Jong-Eun, Shin Eun-Soon, Jang Ji-Hyun, Lee Yeon-Su, Kim Sook-Young, Lee Jong-Young, Han Bok-Ghee, Wu Jer-Yuarn, Kim Kwi-Joo, Park Young-Mi, Seo Eul-Joo, Park In-Sook, Lee Jong-Keuk
Abstract excerpt
Kawasaki disease (KD) is an acute self-limited vasculitis of infants and children that manifests as fever and signs of mucocutaneous inflammation. Coronary artery aneurysms develop in approximately 15-25% of untreated children. Although the etiology of KD is largely unknown, epidemiologic data suggest the importance of genetic factors in the susceptibility to KD. In order to identify genetic variants that...
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