Article
Genome-wide linkage and association mapping identify susceptibility alleles in ABCC4 for Kawasaki disease.
Journal of medical genetics - 1 Jul 2011
Khor Chiea Chuen, Davila Sonia, Shimizu Chisato, Sheng Stephanie, Matsubara Tomoyo, Suzuki Yasuo, Newburger Jane W, Baker Annette, Burgner David, Breunis Willemijn, Kuijpers Taco, Wright Victoria J, Levin Michael, Hibberd Martin L, Burns Jane C
Abstract excerpt
BACKGROUND: Kawasaki disease (KD) is a self limited vasculitis in which host genetics plays a prominent role. To further the understanding of the role of host genetics in KD, a three-stage genetic study was conducted that began with a family linkage study and ultimately involved more than 3000 individuals to identify new genetic contributions to KD susceptibility. METHODS AND RESULTS: A 26-family linkage study...
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