Article
<i>CARD15</i> variants determine a disturbed early response of monocytes to adherent‐invasive <i>Escherichia coli</i> strain LF82 in Crohn's disease
7 Mar 2007
Abstract excerpt
Caspase activation and recruitment domain 15 (CARD15) and Toll-like receptor 4 (TLR4) are respectively intracellular and membrane-bound receptors for bacterial cell wall components [respectively muramyl dipeptide (MDP) and lipopolysaccharide (LPS)]. Polymorphisms in CARD15 and TLR4 have been linked with Crohn's disease (CD). Adherent-invasive Escherichia coli (AIEC) strains with particular adhesion and invasion...
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