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Stratifying macrophages based on their infectious burden identifies novel host targets for intervention during Crohn’s disease associated adherent-invasive <i>Escherichia coli</i> infection

2024-01-10

Abstract excerpt

Bacterial infection is a dynamic process resulting in a heterogenous population of infected and uninfected cells. These cells respond differently based on their bacterial load and duration of infection. In the case of infection of macrophages with Crohn’s disease (CD) associated adherent-invasive Escherichia coli (AIEC), understanding the drivers of pathogen success may allow targeting of cells where AIEC replica...

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Literature Corpus work
eb6f24a8-6a60-508d-b669-bd31b35816f5
DOI
10.1101/2024.01.10.575028
Open publication

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