Article
Genetic Mapping in Mice Reveals the Involvement of Pcdh9 in Long-Term Social and Object Recognition and Sensorimotor Development.
Biological psychiatry - 1 Oct 2015
Bruining Hilgo, Matsui Asuka, Oguro-Ando Asami, Kahn René S, Van't Spijker Heleen M, Akkermans Guus, Stiedl Oliver, van Engeland Herman, Koopmans Bastijn, van Lith Hein A, Oppelaar Hugo, Tieland Liselotte, Nonkes Lourens J, Yagi Takeshi, Kaneko Ryosuke, Burbach J Peter H, Yamamoto Nobuhiko, Kas Martien J
Abstract excerpt
BACKGROUND: Quantitative genetic analysis of basic mouse behaviors is a powerful tool to identify novel genetic phenotypes contributing to neurobehavioral disorders. Here, we analyzed genetic contributions to single-trial, long-term social and nonsocial recognition and subsequently studied the functional impact of an identified candidate gene on behavioral development. METHODS: Genetic mapping of single-trial...
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