Article
Low protective PON1 lactonase activity in an Arab population with high rates of coronary heart disease and diabetes.
Clinica chimica acta; international journal of clinical chemistry - 20 May 2015
Gugliucci A, Caccavello R, Nassar H, Abu Ahmad W, Sinnreich R, Kark J D
Abstract excerpt
BACKGROUND: Recent studies showing that high density lipoproteins (HDL) can effect plaque regression indicate that recent trial failures do not exclude an atheroprotective role of HDL. Instead, they highlight differences between HDL function and measured HDL-cholesterol (HDL-C). PON1 is one key functional activity of HDL. Urban Palestinians have lower HDL-C and a higher incidence and mortality of coronary heart...
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