Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Determinants of variation in human serum paraoxonase activity.

Heredity - 1 Feb 2009

Rainwater D L, Rutherford S, Dyer T D, Rainwater E D, Cole S A, Vandeberg J L, Almasy L, Blangero J, Maccluer J W, Mahaney M C

Abstract excerpt

Paraoxonase-1 (PON1) is associated with high-density lipoprotein (HDL) particles and is believed to contribute to antiatherogenic properties of HDLs. We assessed the determinants of PON1 activity variation using different substrates of the enzyme. PON1 activity in serum samples from 922 participants in the San Antonio Family Heart Study was assayed using a reliable microplate format with three substrates:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aryldialkylphosphatase
Share to Genetic Linkage
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lipoproteins

Share to Mexican Americans

Share to Polymorphism, Genetic

Share to Substrate Specificity

Source

Open in PubMed Open full text

Identifiers

PMID: 18971955
DOI: 10.1038/hdy.2008.110
PMCID: PMC2643132

Genes

PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Determinants of variation in human serum paraoxonase activity.PMID 18971955Read ↗

Genetic and environmental determinants of the PON-1 phenotype.Semantic proximity Read ↗

Determinants of variation in serum paraoxonase enzyme activity in baboons.Semantic proximity Read ↗

Accuracy and biological variation of human serum paraoxonase 1 activity and polymorphism (Q192R) by kinetic enzyme assay.Semantic proximity Read ↗

Determinants of paraoxonase activity in healthy adults.Semantic proximity Read ↗

Multiple QTLs influence variation in paraoxonase 1 activity in Mexican Americans.Semantic proximity Read ↗

Human paraoxonase-1 (PON1): Gene structure and expression, promiscuous activities and multiple physiological roles.Semantic proximity Read ↗

A Multi-Omics Analysis of PON1 Lactonase Activity in Relation to Human Health and Disease.Semantic proximity Read ↗

Clinical and genetic association of serum paraoxonase and arylesterase activities with cardiovascular risk.Semantic proximity Read ↗

Indications that paraoxonase-1 contributes to plasma high density lipoprotein levels in familial hypercholesterolemia.Semantic proximity Read ↗

Biochemical, environmental, and genetic factors associated with paraoxonase (PON1) activity.Semantic proximity Read ↗

Paraoxonase-1 (PON1) activity, but not PON1(Q192R) phenotype, is a predictor of coronary artery disease in a middle-aged Serbian population.Semantic proximity Read ↗

Determination of paraoxonase (PON1) status requires more than genotyping.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.