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Article

Viral genotype correlates with distinct liver gene transcription signatures in chronic hepatitis C virus infection.

Liver international : official journal of the International Association for the Study of the Liver - 1 Oct 2015

Robinson Mark W, Aranday-Cortes Elihu, Gatherer Derek, Swann Rachael, Liefhebber Jolanda M P, Filipe Ana Da Silva, Sigruener Alex, Barclay Stephen T, Mills Peter R, Patel Arvind H, McLauchlan John

Abstract excerpt

BACKGROUND: Chronic hepatitis C virus (HCV) infection of the liver with either genotype 1 or genotype 3 gives rise to distinct pathologies, and the two viral genotypes respond differently to antiviral therapy. METHODS: To understand these clinical differences, we compared gene transcription profiles in liver biopsies from patients infected with either gt1 or gt3, and uninfected controls. RESULTS: Gt1-infected...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25800823
DOI: 10.1111/liv.12830
PMCID: PMC4949513

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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